醫(yī)療/科研特長(zhǎng)：
主要以斑馬魚(yú)為模式動(dòng)物研究人類(lèi)重要疾病相關(guān)基因的功能,。以第一/通訊（共同第一/通訊）作者發(fā)表SCI論文10多篇，其中2篇論文獲得Faculty of 1000推薦,。
研究方向：人類(lèi)疾病相關(guān)易感基因的致病機(jī)制研究
主要教育和工作經(jīng)歷：
2000年12月獲博士學(xué)位,。2001年到2011年期間，先后在新加坡分子和細(xì)胞生物學(xué)研究院（IMCB）從事博士后研究和擔(dān)任研究員,、資深研究員工作,，主要以模式生物擬南芥、斑馬魚(yú)為研究對(duì)象,，研究機(jī)體器官發(fā)育的分子機(jī)理,。2011年12月，作為中山大學(xué)“百人計(jì)劃”引進(jìn)人才到本院工作,，建立了斑馬魚(yú)疾病模式動(dòng)物公共平臺(tái),，開(kāi)展人類(lèi)疾病相關(guān)易感基因的致病機(jī)制研究。
社會(huì)兼職：
廣東省精準(zhǔn)醫(yī)學(xué)應(yīng)用學(xué)會(huì)疾病模型分會(huì)第一屆委員會(huì)副主任委員,。
中國(guó)實(shí)驗(yàn)動(dòng)物學(xué)會(huì)水生實(shí)驗(yàn)動(dòng)物專(zhuān)業(yè)委員會(huì)委員,。
論著：
Wang J#, Guo X, Wang D, Yang S*, Expression patterns of pcbp gene family members during zebrafish embryogenesis. Gene Expr Patterns. 2020 Jan 31; 35:119097. doi: 10.1016/j.gep.2020.119097. [Epub ahead of print]
Zhang M#, Wei Y, Liu Y, Guan W, Zhang X, Kong J, Li H, Yang S*, Wang H*, Metastatic Phosphatase PRL-3 induces Ovarian Cancer Stem Cell Subpopulation through Phosphatase-independent Deacetylation Modulations. iScience 2020 Jan 24;23(1):100766. doi: 10.1016/j.isci.2019.100766.
Shi H#, Li H#, Yuan R#, Guan W, Zhang X, Zhang S, Zhang W, Tong F, Li L, Song Z, Wang C, Yang S*., Wang H*.. PCBP1 depletion promotes tumorigenesis through attenuation of p27 Kip1 mRNA stability and translation. Journal of Experimental & Clinical Cancer Research, 2018, 37：187. ePub，doi: 10.1186/s13046-018-0840-1.
Xu L#, Zhang M, Li H, Guan W, Liu B, Liu F, Wang H, Li Juan, Yang S, Tong X*，Wang H*. SH3BGRL as a novel prognostic biomarker is down-regulated in acute myeloid leukemia. Leuk Lymphoma. 2018, 59(4):918-930.
Gao W#, Chen C#, Zhou T#, Yang S, Gao B, Zhou H, Lian C, Wu Z, Qiu X, Yang X, Alattar E, Liu W, Su D, Sun S, Chen Y, Cheung KMC, Song Y, Luk KKD, Chan D, Sham PC, Xing C, Khor CC, Liu G, Yang J, Deng Y, Hao D, Huang D, Li QZ, Xu C*, Su P*. Rare coding variants in MAPK7 predispose to adolescent idiopathic scoliosis. Human Mutation. 2017, 38(11):1500-1510
Li L#, Shi H#, Zhang M, Guo X, Tong F, Zhang W, Zhou J, Wang H*, Yang S*. Upregulation of metastasis-associated PRL-3 initiates chordoma in zebrafish. International Journal of Oncology, 2016, 48(4):1541-1552.
Tong F#, Zhang M, Guo X, Shi H, Guan W, Wang H* and Yang S*. Expression patterns of SH3BGR family members in zebrafish development. Development Genes and Evolution 2016, 226(4): 287-295.
Zhang W#, Shi H#, Zhang M, Liu B, Mao S, Li L, Tong F, Liu G, Yang S*, Wang H*. Poly C binding protein 1 represses autophagy through downregulation of LC3B to promote tumor cell apoptosis in starvation. International Journal of Biochemistry and Cell Biology. 2016, 73: 127-136.
Qu S#, Liu B, Guo X, Shi H, Zhou M, Li L, Yang S, Tong X*, Wang H*. Independent oncogenic and therapeutic significance of phosphatase PRL-3 in FLT3-ITD–negative acute myeloid leukemia Cancer. 2014, 120(14): 2130-2141.
Yang S #, Aw SS, Chang Q, Korzh S, Korzh V*, and Peng J*. Depletion of Bhmt elevates sonic hedgehog transcript levels to promote pancreatic islet development in zebrafish, Endocrinology, 2011: 152(12):4706-4717.
Korzh S, Winata CL, Zheng W, Yang S, Yin A, Ingham P, Gong Z*. The interaction of epithelial Ihha and mesenchymal Fgf10 in zebrafish esophageal and swimbladder development. Developmental Biology, 2011,359：262–276.
Ma H#, Zhang S, Ji L, Zhu H, Yang S, Fang X*, Yang R*. Mapping and in silico isolation of the EUI1 gene controlling upper internode elongation in rice. Plant Molecular Biology, 2006, 60: 87-94,。
Yang S #, Puah CS, Xie L, Jiang L, Zhang X, Chen L, Ye D*. Over-expression of TPD1 alters the cell fates in the arabidopsis carpel and tapetum via genetic Interaction with EMS1/EXS. Plant Physiology, 2005, 139: 186-191.
Jiang L#, Yang S#, Xie L, Puah CS, Yang W, Sundaresan V, Ye D*. VANGUARD1 encodes a pectin methylesterase that enhances pollen tube growth in the Arabidopsis style and transmitting tract. Plant Cell, 2005, 17: 584-596. (Faculty of 1000 推薦).
Yang S #, Xie L, Mao H, Puah CS, Yang W, Jiang L, Ye D*. 2003. Tapetum determinant 1 gene is required for cell specialization in the Arabidopsis anther. Plant Cell, 15: 2792-2804. (Faculty of 1000推薦).
