醫(yī)療特長(zhǎng):
從事燒傷,、整形,、創(chuàng)面修復(fù)和瘢痕防治的臨床和研究工作。危重?zé)隣C傷,,高壓電擊傷,、化學(xué)燒傷、及放射性損傷等治療,。燒傷后瘢痕及瘢痕疙瘩保守及整形手術(shù)治療,。慢性難治性創(chuàng)面治療。體表腫物,、血管瘤,、黑色素瘤、皮膚癌的整形修復(fù)手術(shù),。自體細(xì)胞移植,,美容修復(fù)。
研究方向:燒傷,、整形,、創(chuàng)面修復(fù)和瘢痕防治
主要教育和工作經(jīng)歷:本科畢業(yè)于中山醫(yī)科大學(xué)臨床醫(yī)學(xué)系,中山大學(xué)外科學(xué)博士,,美國(guó)德州大學(xué)MD Anderson腫瘤中心訪問(wèn)學(xué)者,。中山大學(xué)附屬第一醫(yī)院工作至今。
社會(huì)兼職:國(guó)家衛(wèi)生應(yīng)急處置指導(dǎo)專家,;廣東省杰出青年醫(yī)學(xué)人才(第一批),;國(guó)家、廣東,、江蘇省自然科學(xué)基金,;河北、江西,、四川科技獎(jiǎng)勵(lì)評(píng)審專家,;國(guó)際燒傷學(xué)會(huì)(ISBI)會(huì)員;中華醫(yī)學(xué)會(huì)燒傷外科分會(huì)創(chuàng)面修復(fù)學(xué)組委員,;中國(guó)醫(yī)學(xué)裝備協(xié)會(huì)創(chuàng)面修復(fù)分會(huì)常務(wù)委員,;中國(guó)非公立醫(yī)療機(jī)構(gòu)協(xié)會(huì)損傷與修復(fù)專委會(huì)常委,;中國(guó)研究型醫(yī)院學(xué)會(huì)創(chuàng)面防治與損傷組織修復(fù)專委會(huì)委員;中國(guó)研究型醫(yī)院學(xué)會(huì)生物材料臨床應(yīng)用專業(yè)委員會(huì)委員,;廣東省臨床醫(yī)學(xué)學(xué)會(huì)-華南名醫(yī)專委員會(huì)會(huì)員
論著:
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Application of 3D Printed Models ofComplex Hypertrophic Scars for Preoperative Evaluation and Surgical Planning.Front Bioeng Biotechnol. 2020; 8: 115. doi: 10.3389/fbioe.2020.00115 (IF: 5.12, 通訊作者)
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In situ formed anti-inflammatoryhydrogel loading plasmid DNA encoding VEGF for burn wound healing. ActaBiomaterialia.2019; 100:191-201. (IF: 6.64, 通訊作者)
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Fibronectin precoating wound bedenhances the therapeutic effects of autologous epidermal basal cell suspensionfor full-thickness wounds by improving epidermal stem cells’ utilization. Stem Cell Research & Therapy. 2019;10:0-154. (IF: 4.63, 通訊作者)
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Preparation and characterisation of anovel silk fibroin/hyaluronic acid/sodium alginate scaffold for skin repair.Int J Biol Macromol. 2019;130:58-67. (IF:3.91)
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Efficacy and safety of platelet-richplasma for patients with diabetic ulcers: A systematic review andmeta-analysis. Adv Wound Care (New Rochelle). 2019;8(7):298-308. (IF: 3.71, 通訊作者)
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Three-dimensional digital reconstructionof skin epidermis and dermis. J Microsc. 2017 Dec 14. doi: 10.1111/jmi.12671. (IF: 1.9, 通訊作者)
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Randomized clinical trial of autologousskin cell suspension for accelerating re-epithelization of split-thicknessdonor sites. Brit J Surg. 2017;104:836-842. (IF: 5.59,,通訊作者)
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Transforming growth factor-betainducible early gene-1 (TIEG1) represses Smad7-mediated activation ofTGF-β1/Smad signaling in keloid pathogenesis. J Invest Dermatol. 2017;137:1051-1059. (IF:6.287, 通訊作者)
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Pleiotropic FTY720 is a specific andpotent therapy for hypertrophic scar. JInvest Dermatol. 2017;137:1552-1561. (IF: 6.287, 通訊作者)
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KMT2A promotes melanoma cell growth bytargeting hTERT signaling pathway. Cell Death Dis. 2017;8(7):e2940. (IF:5.965, 通訊作者)
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Composite skin grafting with humanacellular dermal matrix scaffold for treatment of diabetic foot ulcers: arandomized controlled trial. J Am Coll Surg. 2016;222:1171-9. ( IF: 4.307,通訊作者)
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Cleavageand polyadenylation specific factor 4 targets NF-κB/cyclooxygenase-2 signalingto promote cancer growth and progression, Cancer Letters.2016; 381:1-13. (IF: 6.375,,通訊作者)
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E3 ubiquitin ligase Cbl-b negativelyregulates C-type lectin receptor–mediated antifungal innate immunity, J ExpMed. 2016;213: 1555-1570. (IF:11.99)
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Randomizedclinical trial of autologous skin cell suspension combined with skin graftingfor chronic wounds. Brit J Surg 2015;102:e117-23. (IF: 5.59,通訊作者)
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CARD9mediates Dectin-1-induced ERK activation by linking Ras-GRF1 to H-Ras foranti-fungal immunity. J Exp Med. 2014;211:2307-21. (IF:11.99,,共一作者)
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Effectivenessand safety of negative pressure wound therapy for diabetic foot ulcers: ameta-analysis. Plast Reconstr Surg. 2014;134:141-51. (IF: 3.95,,通訊作者)
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Asiaticosidesuppresses collagen expression and TGF-β/Smad signaling through inducing Smad7and inhibiting TGF-βRI and TGF-βRII in keloid fibroblasts. Arch Dermatol Res.2011;303):563-72. IF: 2.15
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Early escharectomy and concurrentcomposite skin grafting over human acellular dermal matrix scaffold forcovering deep facial burns. Plast Reconstr Surg. 2011;127:1533-8. IF: 3.95
專著:
其他主要工作成績(jī)(比如獲獎(jiǎng)情況):
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中國(guó)康復(fù)醫(yī)學(xué)會(huì)科學(xué)技術(shù)獎(jiǎng),一等獎(jiǎng),, 2019,,(第二)
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中華醫(yī)學(xué)會(huì)科技獎(jiǎng),三等獎(jiǎng),, 2019,,(第二)
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廣東省科學(xué)技術(shù)獎(jiǎng)科技進(jìn)步獎(jiǎng),三等獎(jiǎng),,2017. (第二)